It can be caused by a serious injury, muscle disease, or other disorder. It is mostly found in your skeletal muscles and heart, with lesser amounts in the brain. Total creatine kinase levels are reduced in the second trimester of pregnancy. A BUN of 29 is yes elevated, but nothing crazy. stiffness. Kearns AK, Bilbie CL, Clarkson PM, White CM, Sewright KA, O'Fallon KS, Gadarla M, Thompson PD. Muscle damage can also cause levels to rise. Some signs to look out for in addition to a high creatinine level include: Kidney failure refers to a decrease in kidney function and one of the most common causes of high creatinine. I am 58 and recovering from a long illness. She is passionate about releasing the most accurate science and health information available on topics, and she's meticulous when writing and reviewing articles to make sure the science is sound. Available from: National Institute of Neurological Disorders and Stroke [Internet]. Your email address will not be published. Symptoms of a urinary tract blockage can develop quickly or slowly over time depending on the cause. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Epub 2013 Jul 13. CK is a type of protein, known as an enzyme. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Oral creatine supplementation augments the repeated bout effect. Thank you, {{form.email}}, for signing up. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. This article has been viewed 290,823 times. Elevated levels of CK-BB can mean you have some kind of brain injury or have recently had a stroke. An official website of the United States government. You should always contact your doctor or other qualified healthcare professional before starting, changing, or stopping any kind of health treatment. What Are The Benefits Of Exercising Daily. When muscle cells are damaged for whatever reason, the CK enzyme is released Fun fact: The highest creatine kinase on record was over a million and was caused solely by a heavy workout [17]! You recently had a stroke (a blockage of blood flow or bleeding in the brain). Learn more signs of kidney failure. A healthcare professional will draw blood from a vein and send the sample to the laboratory for testing. Avoid smoking. All of our content is written by scientists and people with a strong science background. Elevated levels of CK-MB can mean you have some sort of heart damage. Your healthcare provider suspects you have a muscle disorder. Please enable it to take advantage of the complete set of features! Lose some weight if you are overweight. Ballard KD, Parker BA, Capizzi JA, Grimaldi AS, Clarkson PM, Cole SM, Keadle J, Chipkin S, Pescatello LS, Simpson K, White CM, Thompson PD. Inflammation in the muscle or diseases called myositis, can cause weakness and elevated CK levels. Epub 2007 Jun 14. The precise distribution of serum CK ranges in a wholesome inhabitants is markedly skewed towards increased values and is nongaussian.13 A 97.5% regular threshold is related to a a lot decrease false-positive price and is really useful by the European Federation of Neurological Societies (now the European Academy of Neurology).4 This group additionally recommends pursuing additional investigation just for sufferers whose stage is no less than 1.5 occasions the higher restrict of regular; this threshold ends in solely a small discount in sensitivity. What is the treatment for high levels of creatine kinase? {"smallUrl":"https:\/\/www.wikihow.com\/images\/thumb\/2\/29\/Lower-CPK-Levels-Naturally-Step-9.jpg\/v4-460px-Lower-CPK-Levels-Naturally-Step-9.jpg","bigUrl":"\/images\/thumb\/2\/29\/Lower-CPK-Levels-Naturally-Step-9.jpg\/aid4510115-v4-728px-Lower-CPK-Levels-Naturally-Step-9.jpg","smallWidth":460,"smallHeight":345,"bigWidth":728,"bigHeight":546,"licensing":"