MacRae, W. D. and Towers, G. H. Justicia pectoralis: a study of the basis for its use as a hallucinogenic snuff ingredient. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. Use liquid fertilizers, slow-release or granulated formulas. Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. In Nigeria, the leaf of Justicia carnea is usually prepared with edible vegetables to make soup, boiled separately in water to make tea or prepared by cooking with other medicinal plants for therapeutic purposes. In this study, nutritive potentials and effects of aqueous extract of Justicia carnea leaves on biochemical indices of anaemic male Wistar albino rats were investigated. Saunders; 1995. p. 26873. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. Different drugs are used but many depend mainly on plants and herbal products for its treatment. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. In these groups, from mild to severe order; the renal cortex appears distorted, Renal glomeruli and dillated capsular spaces appeared collapsed with characteristic pyknosis of the mesangial cells, The renal tubules, interstitial spaces, appears distorted with presence of red inflammatory cells, hemorrhagic cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane (red arrows). Inter J Biochem Cell Bio. During the growing season, the justicia (plant) should be watered thoroughly with room temperature water. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. Based on estimation by World Health Organization (WHO), larger percentage (between 80 and 90%) of the worlds population especially in developing countries depends on traditional system of medicine [1, 2]. Generally disease free. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Part shade is the ideal growing condition for Brazilian plumes. Fitoterapia. Brazilian-plumeflowers are best propagated from softwood cuttings. Correspondence to International Journal of Biochemistry Research & Review. The ameliorative effect of Justicia carnea on blood glucose level and lipid profile in alloxan-induced diabetic albino rats was evaluated in a study titled, "Effects of methanol leaves extract . One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. You can add milk or honey for taste before drinking. Absorbance reading was taken at 620nm regularly at an interval of 1min against reagent blank. It is very rich in iron, a major component is RBC hemoglobin. The flowers are slightly fragrant and mostly sterile. There is however little publications available on the pharmacological properties of the herbal plant. Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. The major use of Justicia carnea leaves is to improve blood production. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. As declared by all authors, no competing interests exist. 3rd ed. BMC Complem Altern Med. Only plants will be removed from the collection. The liver and kidneys were excised and rinsed immediately in a normal saline (0.9% Nacl) to remove blood stain, dried between layers of Whatman filter paper, weighed and homogenized to obtain the supernatant for biochemical analysis. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Vitamin C and E are antioxidants. This is attributed to the anti-hyperlipidaemic properties of the plant. Karigidi is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. The roots and the leaves possess medicinal values and have been used in treating several diseases. This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. The blood stimulating effects could be due to the presence of dietary bioactive constituents that stimulate activities of haematopoietic cells and stabilization of blood in circulation [21]. In phase two, three rats were separated into 3 groups of one rat per group. This amazing, Coriander seeds as well as the leaves are widely used as spices in flavoring foods and drinks, and, Cashew leaves: health benefits and side effects of Anacardium occidentale, Fig leaves tea: Amazing benefits and best recipes, Negro pepper: 12 health benefits of uda seed and side effects. Methods. For some, the boiling method is preferred while for others, soaking in hot water is more convenient. Chemical constituents and biological activities of species of Justicia a review. Rich on haematological and biochemical parameters in healthy Wistar rats. These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Haematological and biochemical studies on Justicia carnea leaves extract in phenylhydrazine induced-anemia in albino rats. Niger J Physiol Sci. This encourages better flowering and bushier and denser new growth. One of the health benefits of justicia carnea is in boosting immune system. The LD50 of extract was greater than 5000mg/kg body weight. Inter J Pharm Sci Res. Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. This post was last modified on January 2, 2023 5:23 pm. https://doi.org/10.13040/IJPSR.0975-8232. View abstract. 50mg/kg-1200mg/kg treatments relative to control showed varied degree of hepatic injury that is dose dependent. Uses, Benefits, Cures, Side Effects, Nutrients in Justicia Betonica. In subacute study, rats were randomized into six groups of five rats per group: Group 1 (control) received distilled water, group 2, 3, 4, 5, 6 received 50, 100, 500, 800 and 1200mg/kg body weight of J. carnea ethanol extract once daily using oral gavage. Join now and start creating your dream garden! Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. Group 2, 3, 4, 5, 6 were respectively administered orally with 50, 100, 500, 800 and 1200mg/kg body weight of JCEE once daily for 14days using an oral gavage. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. While not necessary, prune the justicia (plant) freely to maintain the desired shape and size. 1.3.1 Aetiologyof Anaemia Anaemia may be due to a single factor such as a nutritional deficiency or multifactorial (McEvoy, 2013). Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. Justicia carnea is commonly cultivated and grown as an ornamental potted plant. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. degree in Biochemistry fromUniversity of Ado-Ekiti, Ekiti State, Nigeria and University of Ibadan, Nigeriarespectively. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. Justicia pectoralis might have many different effects in the body. Anal Biochem. Justicia carnea belongs to the family- Acanthaceae.

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