Caution students against drinking any of the liquids used in this activity, and have them wash their hands at the end of the activity. The cookie is used to store the user consent for the cookies in the category "Other. By exchanging bodily fluids with their friends, it is likely that several more students are now "infected with HIV." Students can dive into the pandemic of 2020 and relate the information learned in this activity to how COVID-19 spread so quickly. COVID-19 Learning Note: The novel coronavirus that causes COVID-19 has not previously been introduced to the human population, so no one in the world has prior immunity to it. Students may be interested in reading about other epidemiology case studies and how epidemiologists go about their work. (Grades Objective: Students will understand the dynamics of the transmission of diseases by taking part in a "hands-on" simulation. In this simulation, you'll play the part of a pathogen and try to establish an infectious colony within a human body. The human immune system, germs, and practicing healthy hygiene habits have become topics our children have become very familiar with. The immune (pronounced: ih-MYOON) system attacks germs and helps keep us healthy. **Answer the 10 question Immune System quiz. Lymphatic organs, cells, and antigens are addressed. National Institute of Health, Word on Health, October 2000, "Stress and Disease," http://www.nih.gov/news/WordonHealth/oct2000/stressfigure.htm, Wikipedia, The Free Encyclopedia. Give some examples from history, such as the Plague, AIDS, Ebola, H1N1, or make reference to movies such as Outbreak. VLS Courses include practical tools and resources to use within programs to support high-quality, research-informed practices. Younger students will walk away with new knowledge if an activity may appear above grade level. Fill the other cups about one-quarter full with water. Lawrence Berkeley National Laboratory, Currents, "Computers Identify T Cell Turn-Ons," edited by Pamela Patterson, October 3, 2003, http://www.lbl.gov/Publications/Currents/Archive/view-assets/Oct-03-2003/t-cell2.jpg. To do the activity as a class, divide students into antibodies and antigens." White blood cells (macrophages, neutrophils and natural killer cells) these students are in charge of standing inside the classroom, by the door, to prevent invading antigens from proceeding further into the room. Chemical engineers develop vaccinations and antibiotics that help our immune systems fight some of the most threatening germs. Ask each student to pick a card with their eyes closed; it is important that students do not know who their matching antigen or antibody is before the start of the game. 6 - Bacteria are simple, completely independent, single-celled organisms that are able to eat and reproduce (think of them as fish swimming through your body). Immune System Virtual Lab Webquest. Have a student volunteer put a drop of phenolphthalein in each test tube, and students will then be able to see how close they got to determining the original sources of the virus. On a grander scale, the game gives them a deeper appreciation of their bodies. PS: We do not share personal information or emails with anyone. Antigens (represented by the colored shapes) are proteins found on the surface of pathogens, such as viruses, bacteria, and other foreign invaders to the body. Encourage wild ideas and discourage criticism of ideas. (Listen to student answers.) If you know of other sites, please share in the comments! Published Point out that epidemiologists are scientists and medical doctors who try to solve puzzles such as this, and epidemiology is a branch of medicine that is concerned with the causes, spread, and control of diseases in populations. These cookies ensure basic functionalities and security features of the website, anonymously. function init() { window.wSlideshow && window.wSlideshow.render({elementID:"233625115771570498",nav:"thumbnails",navLocation:"bottom",captionLocation:"bottom",transition:"fade",autoplay:"0",speed:"5",aspectRatio:"auto",showControls:"true",randomStart:"false",images:[{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-24-20-pm.png","width":400,"height":303,"fullHeight":615,"fullWidth":812},{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-23-41-pm.png","width":400,"height":271,"fullHeight":746,"fullWidth":1100},{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-23-07-pm.png","width":301,"height":284,"fullHeight":284,"fullWidth":301},{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-24-59-pm.png","width":400,"height":363,"fullHeight":458,"fullWidth":504},{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-28-04-pm.png","width":400,"height":301,"fullHeight":618,"fullWidth":820},{"url":"8\/0\/9\/0\/80904242\/screen-shot-2018-02-26-at-7-29-35-pm.png","width":400,"height":207,"fullHeight":319,"fullWidth":617}]}) } Skin (or mucus or cilia): skin is an effective barrier to the entry of micro-organisms, while cilia, tears, sweat, saliva, mucus and earwax trap or wash micro-organisms away. Any differences? The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. High School THE HUMAN IMMUNE SYSTEM (UNIT 1) : Lesson 3 The Adaptive Immune System The Adaptive Immune System Students learn about the specific nature of responses generated by the adaptive immune system. The article also tells the story of a more contemporary outbreak in west Africa, which is particularly interesting because of the role prevailing cultural practices can play in the transmission of a disease. Build a Digestive System Maze. 9. (function(jQuery) { Keywords: Biology, Immune system, Infectious diseases. It acts as a defense against foreign particles that want to enter your body, protects against some poisons and suppresses cancer cells. The lymph system filters lymph and removes bacteria. Explain how testing for antibodies can inform a medical diagnosis. Use an oral and written argument supported by evidence to support or refute an explanation or a model for a phenomenon. One to two 50-minute class periods, depending on implementation. Make sure to read both pages before you move on to the quiz. Please read the information about class size in step 3 of the Conducting the Simulation section (below) before you start! AIDS can be transmitted sexually as well as through blood contact. Once a body has experienced and recovered from certain diseases, it rarely suffers from them again (such as chicken pox or measles) because the body recognizes the virus and eliminates it before it can do anything. HTML 5 compatible browser needed to view video. How might students change the model to make it more accurate? . Please visit http://www.biology.duke.edu/cibl/ for information about CIBL and other resources for K-12 science and math teachers. Pass the flashcards to the next team. Sign up to receive a free glow stick lab sent to your inbox! DGE 0338262. Do you agree with this alignment? 3 - Unfortunately, no cure is known for HIV or AIDS, and a person who has one or both of the diseases eventually dies; however, chemical engineers have discovered treatments for the two diseases and are striving to discover a cure. Students learn about the major components and functions of the immune system and the role engineers play in keeping the body healthy through the design of medical care such as vaccinations and antibiotics. Let me help your students with experimental design! Did you know that inside your body you have a tiny "army" that protects you from invaders? Bacteria are independent little creatures that roam around inside your body, while viruses invade your healthy cells to multiply since they are not actually alive. If they are right, they pass the card on to another team. Immune system questions. Also, consider at which times you might have students assess whether aspects of this simulation accurately model the immune response. Explain how a virus replicates itself once it attaches to a host cell. We are all constantly exposed to microorganisms, some of which can make us sick. If people have their spleens removed due to illness or injury, they are at much higher risk of becoming ill in the future. ); available from educational material suppliers or online at. While bacteria often grow in the fluids between your cells, and can reproduce and spread through the body via the bloodstream, viruses have a different strategy. What do you notice about the antibodies? Viruses, on the other hand, are not really alive. Reproduction of material from this website without written permission is strictly prohibited. The teacher is in charge of keeping the door of the classroom closed (the door remains unlocked but the teacher must keep the door from being opened by members of the opposite team, who are standing outside the classroom) until a cut or a breach in the bodys mucus membrane is simulated. 'Ready, set, infect!' is a role-playing game for middle-school science classrooms (ages 11-14). Send-a-Problem: Divide the class into teams of two or three students each and have them write their own questions about the immune system. Any differences? They also have 4 virtual labs that deal with DNA. They should include terms from each of the three lines of defence in their diagrams. The human immune system reacts quickly when a virus invades the body, shown in Figure 2 below. We also use third-party cookies that help us analyze and understand how you use this website. Have the bag engulf, ingest (gobble up), and eliminate these large globs of material. List several invaders of the immune system, including viruses and bacteria. Necessary cookies are absolutely essential for the website to function properly. If you have 20 or fewer students, use only two "infected" cups (and test tubes) for the simulation, instead of three. T cell: A cell that matures in the thymus and is involved in an immune response that does not have to do with antibodies. They love doing older school. Consider how you might adapt this activity so the simulation includes the body having the memory of a virus through vaccination, thereby creating a rapid immune response that generally avoids illness. Describe what happens to the immune system in space. This results in cuts taking longer to heal and colds lingering longer than usual due to the presence of stress. The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. So, dont hesitate to bring all of the ages together in your homeschool to do some of the activities. that shapes our lives. Materials required for for antibodies immune system activity include: magnetic tape, a ruler, scissors, plastic wrap, twist ties, a digital scale, a glass jar with a lid, table salt, iron filings, a measuring cup, a tablespoon, and a piece of paper and pen. To make distribution of the cups easier, have only three or four students select their cups at a time. antibody, antigen, autoimmune disease, enzyme-linked immunosorbent assay (ELISA), humoral immunity, infection, laboratory technique, lupus, screening. Anyone who has seen live footage of a human white blood cell chasing and capturing a bacterium in the body would think he or she was witnessing a game of cops and robbers. When all students are finished, each student should have shared liquids with exactly three other students. B cells secrete millions of antibodies (proteins that identify and neutralize foreign agents, such as bacteria and viruses) that mark foreign antigens for destruction by other immune cells. Teaching through role-playing games allows students to engage in the messy nature of science. In space, astronauts lose bone mass (up to 2% per month), which ultimately affects the production of white blood cells, which help attack the body's invaders. The enzyme-linked immunosorbent assay (ELISA) is a laboratory technique that detects and measures specific proteins. What do you notice about the antigens? In response, the bodys immune system launches a cascade of complex processes that end up with the antigen from the outside invader binding with a matching antibody. These digestive juices help to continue the chemical digestion of food. Number the test tubes in the same way. This process is referred to as self/non-self recognition (if it fails, it can cause an infection or an autoimmune diseases where the immune system attacks the body instead of pathogens). Biomedical engineers and epidemiologists must understand how a virus infects the cells in our bodies and how our immune system reacts to the invasion in order to create vaccinations, protective devices, and procedures to keep us safe.
